Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00932Fluoxetine--
BADD_D00952Folic acid0.000823%
BADD_D00978Fulvestrant0.008090%
BADD_D00979Furosemide0.000729%
BADD_D00981Gabapentin--
BADD_D00998Gallium cation--
BADD_D01000Gallium nitrate--
BADD_D01003Ganciclovir--
BADD_D01008Gefitinib0.004529%
BADD_D01009Gemcitabine0.014919%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01038Goserelin0.001471%
BADD_D01060Heparin--
BADD_D01062Hepatitis b immune globulin (human)--
BADD_D01081Hydralazine0.000663%
BADD_D01083Hydrochlorothiazide0.000155%
BADD_D01099Hydroxocobalamin--
BADD_D01110Hydroxyurea0.001598%
BADD_D01119Ibrutinib0.031436%
BADD_D01120Ibuprofen0.000037%
BADD_D01130Idelalisib--
BADD_D01133Ifosfamide--
BADD_D01135Iloprost--
BADD_D01136Imatinib0.018382%
BADD_D01137Imatinib mesylate--
BADD_D01142Imiquimod0.003476%
BADD_D01159Insulin (human)--
BADD_D01167Interferon alfa-2b--
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